Revolutionary biofilms fighting nosocomial infections
Development of self-defensive antimicrobial and antifungal polysaccharide films.
Hip replacements, aortic valves, pins ... the use of surgical implants is common but can lead to serious complications such as nosocomial infections. Bacteria with multi-resistances to antibiotics bind to the surface of the prostheses and are difficult to dislodge. To combat them, a self-defensive coating containing a molecule that's lethal for bacteria and yeast has been developed. The pathogen that tries to cling to the surface secretes an enzyme whose activity causes the release of the antimicrobial. Toxic to pathogens but not to the cells of the body, these biofilms are promising candidates for future treatment applications.